Persufflation (gaseous oxygen perfusion) as a method of heart preservation

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Persufflation (gaseous oxygen perfusion) as a method of heart preservation

Persufflation (PSF; gaseous oxygen perfusion) is an organ preservation technique with a potential for use in donor heart preservation. Improved heart preservation with PSF may improve outcomes by maintaining cardiac tissue quality in the setting of longer cold ischemia times and possibly increasing the number of donor hearts available for allotransplant. Published data suggests that PSF is able...

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Persufflation (or gaseous oxygen perfusion) as a method of organ preservation.

Improved preservation techniques have the potential to improve transplant outcomes by better maintaining donor organ quality and by making more organs available for allotransplantation. Persufflation, (PSF, gaseous oxygen perfusion) is potentially one such technique that has been studied for over a century in a variety of tissues, but has yet to gain wide acceptance for a number of reasons. A p...

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Coronary oxygen persufflation combined with HTK cardioplegia prolongs the preservation time in heart transplantation.

BACKGROUND One of the most restricting factors remaining in heart transplantation is the limited myocardial ischemia time. A new approach towards the prolongation of this time is the combination of primary cardioplegic arrest followed by continuous coronary oxygen persufflation (COP) with gaseous oxygen. METHODS This technique was applied in pig hearts, which we transplanted orthotopically af...

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Oxygen persufflation as adjunct in liver preservation (OPAL): Study protocol for a randomized controlled trial

BACKGROUND Early graft dysfunction due to preservation/reperfusion injury represents a dramatic event after liver transplantation. Enhancement of donor organ criteria, in order to cope with the ever increasing donor shortage, further increases graft susceptibility to ischemic alterations. Major parts of post-preservation injury, however, occur at the time of warm reperfusion but not during isch...

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Donor Heart Preservation and Perfusion

Due to its technically simple and easily reproducible nature cold static preservation is still the current gold standard for myocardial protection in between donor explantation and recipient implantation. It allows “safe” overall ischemic periods of up to 4 hours with a primary graft failure rate less than 2%. Additional measures such as second rinsing or leucocyte depleted in-situ reperfusion ...

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ژورنال

عنوان ژورنال: Journal of Cardiothoracic Surgery

سال: 2013

ISSN: 1749-8090

DOI: 10.1186/1749-8090-8-105